Recently, the glycoproteomic analysis of intact glycopeptides has emerged as an effective approach to decipher the glycan modifications of glycoproteins at the site-specific level. A rapid method to e
Age groups are stratified 60. * the value for glycoform E is already a bisecting/non-bisecting ratio as it is normalized on its non-bisected counterform B.
The α1,6-fucosyltransferase (encoded by FUT8 gene) is the key enzyme transferring fucose to the innermost GlcNAc residue on an N-glycan through an α-1,6 linkage in the mammalian cells. The presence of
Despite the important roles of protein sialylation in biological processes such as cellular interaction and cancer progression, simple and effective methods for the analysis of intact sialylglycopepti
We report α-hydroxyl aldehyde–2-aminooxazole conjugation (HAAC), a bioorthogonal ligation platform that enables selective biomolecular labeling and functional modulation under physiological conditions
