<b>Age-related decline of nuclear envelope LINC complex drives neuronal aging</b>

<b><i>3M.pc1.bw</i></b>, <b><i>20M.</i></b><b><i>pc1.</i></b><b><i>bw</i></b> and <b><i>20M+Sun1.</i></b><b><i>pc1.</i></b><b><i>bw</i></b> are BigWig files containing PC1 values obtained from principal component analysis (PCA) of Hi-C data across the genome. These files can be visualized using tools such as the UCSC Genome Browser or IGV.<b><i>3M.normalized.corrected.cool</i></b>, <b><i>20M.normalized.corrected.cool</i></b> and <b><i>20M+Sun1.normalized.corrected.cool</i></b> are COOL files containing normalized and corrected Hi-C data. These files are used for the following visualizations:Contact map<i>for sample in 3M 20M 20M+Sun1; do</i><i>hicMergeMatrixBins -m ${sample}.normalized.corrected.cool -o ${sample}.normalized.corrected.nb20.cool -nb 20</i><i>hicPlotMatrix --matrix ${sample}.normalized.corrected.nb20.cool --outFileName ${sample}.contactmap.png --rotationX 45 --fontsize 6 --log1p --dpi 300</i><i>done</i>Distance-dependent contact frequency<i>hicPlotDistVsCounts --matrices 3M.normalized.corrected.cool 20M.normalized.corrected.cool 20M+Sun1.normalized.corrected.cool --plotFile distvscount.genome.png --labels '3M' '20M' '20M+Sun1'</i><i>hicPlotDistVsCounts --matrices 3M.normalized.corrected.cool 20M.normalized.corrected.cool 20M+Sun1.normalized.corrected.cool --plotFile distvscount.chromsome.png --labels '3M' '20M' '20M+Sun1' --perchr</i><br><br>