Germond et al. 2018a-Raman & gene expression datasets.xlsx

This file include 2 datasets used in Germond et al. 2018 Biological samples: Eleven E. coli strains described in Suzuki et al. 2014 Nature Communication. One strain is the parental strain MDS42 and 10 others are evolved strains that acquired a resistance against antibiotic drugs during a 3 month period of evolution. Cell lines are labelled according to the antibiotic drug they were evolved in. 1st dataset: Raman spectral dataset of 624 independent populations of Escherichia coli measured 5 times each by Raman spectroscopy. Average data of the five measurements are presented. Measurements were performed using a 532 nm excitation wavelength using 5 sec exposure per measure. 2nd dataset: Transcriptome data of E coli strains as measured by microarray. The log10-transformed expression levels after quantile normalization are presented. Genes for which the expression value was below 2.0 were removed, as recommended by the manufacturer, leaving 2613 genes (out of 4600+) in the dataset. Please refer to Germond et al. 2018a Communication Biology when using this dataset. See the publication for the detailed measurement procedures.