MTHFS
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1315743
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资源简介：
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
本基因编码的蛋白质为一种酶，催化5-甲酰四氢叶酸转化为5,10-亚甲基四氢叶酸，该物质为还原型叶酸的先体，参与一碳代谢过程。编码蛋白活性的增加可能导致叶酸转换率的上升及叶酸的耗竭。针对该基因，已发现三种转录变体，分别编码两种不同的异构体。[由RefSeq提供，2011年6月]
提供机构：
Rat Genome Database
