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Time-course of HCoV-229E infection of A549 cells

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE89159
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The aim of the experiment is to identify kinetic changes in host gene expression upon infection of A549 lung epithelial carcinoma cells with human corona virus HCoV-229E as compared to unifected cells. Negativ controls include infections with heat-inactivated virus. Positive controls include treatment of cells with human IL-1alpha (10ng/ml) for 1h. All experiments have been performed at 33°C which is required for sufficient viral entry/replication. Single-color hybridizations of RNA from HCoV.229E infected A549 cells, time course (16,24,48 h), with time-mathched controls plus two additional controls (untreated and IL1-treated). No replicates.
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2018-03-27
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