Figure 2: The structural basis of protective and nonprotective human monoclonal antibodies targeting the parainfluenza virus type 3 hemagglutinin-neuraminidase
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https://figshare.com/articles/dataset/Figure_2_The_structural_basis_of_protective_and_nonprotective_human_monoclonal_antibodies_targeting_the_parainfluenza_virus_type_3_hemagglutinin-neuraminidase/27904791/1
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. Fusion inhibition of mAbs from each site was assessed by transfecting Vero-SLAM cells with either HN or F and GFP 3 hrs prior to adding mAb. Syncytia formation was visualized 24 hours following transfection and fusion inhibition was evaluated by comparison to the PBS-treated control. Previously identified anti-F mAb PIA174 was used as a positive control.
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2024-11-25
