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Next generation sequencing for the prenatal (30--90 day) testosterone (T) treatment and its effect on gene expression in fetal day 90 (D90) and adult year 2 (Y2) ovaries.

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144589
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A direct correlation between changes in epigenetic marks and gene expression in adult ovaries from prenatally- T-treated sheep establishes epigenetic changes as one of the underlying causes for differential expression of genes in PCOS ovary. Using DESeq2 R package, differentially expressed genes (DEGs) were identified between control (n = 3) and T- treatment (n = 3) for fetal D90 and control (n = 3) and T (n = 4) for adult Y2, respectively
创建时间:
2020-03-09
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