Frequencies and HINT scores of water molecules at protein-protein interfaces with respect to backbones and sidechains of interacting amino acid residues.

Notes: aSame as Table 3; bWeighted count is calculated as ∑n { |Ai|/∑i |Ai| }, where Ai are the interaction HINT scores for the backbone or sidechain by residue type (i) interacting with water n; cHINT scores are averaged two ways: first, over all waters in set or Relevance subset, second, by frequency of the backbone or sidechain contribution (weighted count) of that residue type in set or Relevance subset; dFor Gly (and all other residues) the CA atom is considered part of the backbone, thus Gly has no sidechain.