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Paternal overdiet drives intergenerational transmission of metabolic disorders through sperm epigenetic alteration [MeDIP-Seq]

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NIAID Data Ecosystem2026-03-11 收录
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We using a mouse model of paternal famine to simulate famine, our data show that paternal famine increases the susceptibility to metabolic disease in offspring through gametic epigenetic alterations. Sperm DNA profiles of 12 week old control male F0 and Famine male F0 mice were generated by deep sequencing

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2019-06-13
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