Additional file 4 of Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies
Extracellular amyloid-Ã (AÃ) deposition as neuritic plaques and intracellular accumulation of hyperphosphorylated, aggregated tau as neurofibrillary tangles (NFT) are two of the characteristic hallm
This project is a pilot study, in collaboration with Maria Grazia Spillantini and Mariangela Iovino (Cambridge Centre for Brain Repair), to investigate the utility of IPS-derived neurons for the study
Significantly enriched proteins in pull-down samples described in Figs 5 and S5 with log2 fold change > 2 are listed in descending order. A darker color shade represents higher values. SneRING (SNE_A1
Additional file 5: Table S3. Sheet 1: Consolidated list of proteins identified as AKT1 interactors from AKT1 pull down samples after targeting HA and Strep tags. Interacting partners of AKT1 were anal
The endocannabinoid system (ECS) consists particularly of cannabinoid receptors 1 and 2 (CB1 and CB2), their endogenous ligands, and enzymes that synthesize and degrade their ligands. It acts in a var