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Concise Total Synthesis of (−)-8-Epigrosheimin

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NIAID Data Ecosystem2026-03-07 收录
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https://figshare.com/articles/dataset/Concise_Total_Synthesis_of_8_Epigrosheimin/2630452
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A highly efficient route was developed to synthesize (−)-8-epigrosheimin in four steps from aldehyde 2 based on a substrate-controlled method. The key steps of the synthesis included (1) a stereo- and regioselective allylation addition, (2) an intramolecular translactonization, and (3) an aldehyde-ene cyclization.
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2011-07-15
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