Nedd4

ENCODES a protein that exhibits ubiquitin-protein transferase activity; beta-2 adrenergic receptor binding (ortholog); enzyme binding (ortholog); INVOLVED IN immune response; protein K63-linked ubiquitination; regulation of dendrite morphogenesis; PARTICIPATES IN vascular endothelial growth factor signaling pathway; endocytosis pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH muscular atrophy; autistic disorder (ortholog); Bloom syndrome (ortholog); FOUND IN glutamatergic synapse; microvillus; cell cortex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; 2-methoxyethanol

编码一种表现出泛素-蛋白转移酶活性的蛋白；β-2 肾上腺素受体结合（同源）；酶结合（同源）；参与免疫反应；蛋白 K63 连接的泛素化；树突形态发生调控；参与血管内皮生长因子信号通路；内吞作用途径；泛素/蛋白酶体降解途径；与肌肉萎缩相关；孤独症（同源）；布鲁姆综合征（同源）；存在于谷氨酸能突触；微绒毛；细胞皮质（同源）；与 2,3,7,8-四氯化二苯并-对二恶英、2-氨基-2-脱氧-D-葡萄糖吡喃糖、2-甲氧基乙醇相互作用。