The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells

NIAID Data Ecosystem2026-03-08 收录

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RBM47可变剪接调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA252381 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

创建时间：

2014-06-10

Identification of LncRNA Expression Signatures for breast cancer brain metastasis (BCBM)

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lncRNA

To identify BCBM-relevant lncRNAs, we assessed the expression profiles of lncRNAs in parental MDA-MB-231 (231-PAR) cells and isogenic brain metastatic cells (231-BRN), which were isolated from brain-s

NIAID Data Ecosystem80

Gene expression profile at single cell level of cerebrospinal fluid cells derived from one breast cancer leptomeningeal metastases patient. Gene expression profile at single cell level of cerebrospinal fluid cells derived from one breast cancer leptomeningeal metastases patient

单细胞转录组学

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Cerebrospinal fluid cells derived from one breast cancer leptomeningeal metastases patient Overall design: Cerebrospinal fluid cells were isolated by Fluorescence-activated cell sorting (FACS) accordi

NIAID Data Ecosystem40

YTHDF3 Induces the Translation of m6A-enriched Metastasis-associated Gene Transcripts to Promote Breast Cancer Brain Metastasis [RIP-Seq]. YTHDF3 Induces the Translation of m6A-enriched Metastasis-associated Gene Transcripts to Promote Breast Cancer Brain Metastasis [RIP-Seq]

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m6A甲基化调控

Brain metastasis is a major cause of cancer mortality, but its molecular mechanisms are severely understudied. We found that YTHDF3 overexpression clinically correlates with brain metastases in breast

NIAID Data Ecosystem10

The lncRNA DANCR promotes breast cancer brain metastasis by acting as a ceRNA for miR-758-3p to regulate PTGS2 expression

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ceRNA调控

Brain metastases in breast cancer patients are correlated with markedly lower survival rates than extracranial metastases, highlighting the critical necessity for identifying novel therapeutic targets

中国科学数据2026-04-03 更新40

Median survival of intracranial breast cancer model.

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药物疗效评估

Median Survival of an intracranial breast cancer model treated with Control (PBS), non-liposomal doxorubicin (NonL-doxo) versus PEGylated Liposomal Doxorubicin (PLD).*P value for NonL-doxo vs. PLD = 0

Figshare2015-12-02 更新10

The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells

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