Targeted proteomics analysis of Cutaneous Lupus Erythematosus patient interstitial skin fluid and plasma (Inflammation panel data)

We performed a targeted proteomics analysis of Cutaneous Lupus Erythematosus (CLE) patient blister biopsies and plasma using Olink Proteomics panels to validate the blister biopsy technique using previously identified biomarkers, to confirm protein-level expression of biomarkers previously identified at the RNA level, and to identify new biomarkers of disease. Protein biomarkers in lesional and nonlesional interstitial skin fluid and blood plasma from 4 CLE patients and 3 healthy controls were measured using the Olink Proteomics Target 96 Inflammation panel v.3022.