Inception characteristics of subjects in CATCH and of patients with available serial radiographs.

* No significant differences identified except for anti-CCP (p<0.001); Swollen Joint Count (p<0.001), non-biologic DMARD combination therapy (p<0.01) and Steroid exposure (p = 0.003). ** Comorbidities recorded include: angina/heart attack, asthma, other heart problems, hypertension, cerebrovascular disease/accidents, anemia, bronchitis/emphysema, hypercholesterolemia, bowel disease, stomach ulcer, liver disease, kidney disease, tuberculosis, cancer, psoriasis, thyroid disease, diabetes, hepatitis, chronic infection, osteoarthritis, lupus, osteoporosis, back/spine problems, fibromyalgia, fractures, depression, mental illness, alcoholism, severe allergies, thromboembolic disease, Parkinson disease, migraines, seizures/epilepsy, gynecologic/prostate problems, HIV, herpes and/or cold sores. *** Reported by site investigator; not from central reader Results are reported as a Mean (SD) unless otherwise noted. RF, rheumatoid factor; Anti-CCP, anti-cyclic citrullinated peptide; ESR, erythrocyte sedimentation rate; DAS28, disease activity score using a 28-joint count; HAQ Health Assessment Questionnaire; DMARD, disease modifying anti-rheumatic drug