Treatment of rheumatoid arthritis patients with chaperonin 10. Treatment of rheumatoid arthritis patients with chaperonin 10

Trial described in Lancet. 2006 Sep 2;368(9538):855-63. Rheumatoid arthritis patients were treated with chaperonin 10, with a dose of 10 mg rCpn10 i.v. twice weekly for 56 days. Blood samples were collected before and after treatment. Microarray analysis described in Hirata et al., Early pregnancy factor, chaperonin 10 and rheumatoid arthritis; the story unravels. J Transl Sci 2018. Overall design: Microarray data from 4 deidentified patients enrolled in the aforementioned trial. Samples were collected before and after treatment with CPN10, making a total of 8 samples.