iScience_Heo_et_al_2025

NIAID Data Ecosystem2026-05-02 收录

阿尔茨海默病神经保护机制

星形胶质细胞钙信号

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https://data.mendeley.com/datasets/cjv5xz7bwf 数据链接链接失效反馈

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资源简介：

The excel file contains source data for Heo et al. 2025 published in iScience titled "Impaired neuromodulator crosstalk delays arousal-dependent astroglia Ca2+ activation in mouse models of Alzheimer's disease".

创建时间：

2025-07-08

Table_1_Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer’s Disease Model.XLSX

阿尔茨海默病神经保护机制

海马γ振荡与中间神经元功能

Recent studies have implicated impaired Parvalbumin Fast-Spiking Interneuron (PVIN) function as a precipitating factor underlying abnormalities in network synchrony, oscillatory rhythms, and cognition

NIAID Data Ecosystem80

Data_Sheet_1_Calcium Dynamics in Astrocytes During Cell Injury.PDF

星形胶质细胞钙信号

细胞损伤吞噬

The changes in intracellular calcium concentration ([Ca2+]) following laser-induced cell injury in nearby cells were studied in primary mouse astrocytes selectively expressing the Ca2+ sensitive GFAP-

NIAID Data Ecosystem30

Differences in kinetic parameters for Ca2+ responses evoked in cerebellar and cortical astrocytes.

星形胶质细胞钙信号

神经细胞生理学

Cerebellar and cortical astrocytes stimulated with 1 mM ATP, glutamate (glu) and histamine (his) were compared. Values of difference (D) were calculated as outlined in Methods. Lower values indicate a

Figshare2015-12-02 更新10

Astrocytic calcium traces from organotypic hippocampal slices

星形胶质细胞钙信号

显微成像

Each column of the file (ROI) corresponds to an individual calcium trace, expressed as ΔF/F0. Recordings were performed using confocal microscopy on organotypic hippocampal slices (Gähwiler type), wit

Figshare2019-07-18 更新30

Table_9_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xls

阿尔茨海默病神经保护机制

Jak-STAT信号通路

Despite extensive research on Alzheimer’s disease (AD), its diagnosis and treatment remain challenging, and no effective therapies are currently available. Amyloid β (Aβ) extracellular plaques and int

NIAID Data Ecosystem20

iScience_Heo_et_al_2025

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