IL-6 has been shown to be required for somatic cell reprogramming into induced pluripotent stem cells (iPSCs). However, how the cytokine is regulated and if it plays a role during embryo development r

NIAID Data Ecosystem50

Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]. Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]

干细胞重编程

染色质可及性调控

Chemical induction of pluripotency (CIP) is an ideal way to reprogram cell fate, but remains poorly understood. Here we report the development of an efficient CIP protocol and the chromatin accessibil

NIAID Data Ecosystem40

Additional file 8: of Genome-wide transcriptome analyses of developing seeds from low and normal phytic acid soybean lines

大豆植酸遗传调控

基因表达比较

Statistical test results for qPCR and RNA-Seq data comparison. The stage-specific data for each gene was tested for normality and sample variances using Shapiro-Wilkâ s test and F-test, respectively.

Figshare2016-12-15 更新80

Transcription factor NKX3-1 is required for reprogramming to pluripotency and can replace OCT4 in mouse and human iPSC induction [ATAC-seq]. Homo sapiens

干细胞重编程

转录因子功能

Resolution of early molecular events preceding endogenous OCT4 activation is critical to understanding the mechanism of reprogramming somatic cells to induced pluripotent stem cells (iPSCs), yet captu

NIAID Data Ecosystem40

Global gene expression analysis in murine iPS cells derived with mouse and human Nanog orthologs

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