Crystal structure of fragment 2-(Benzo[d]thiazol-2-yl)acetic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain
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Crystal structure of fragment 2-(Benzo[d]thiazol-2-yl)acetic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain Descriptor: (1,3-benzothiazol-2-yl)acetic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... Authors: Harding, R.J, Halabelian, L, Ferreira de Freitas, R, Ravichandran, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Structural Genomics Consortium (SGC) Deposit date: 2018-02-11 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors. J. Med. Chem., 61, 2018
结合于HDAC6锌指结构域泛素结合口袋的2-(苯并[d]噻唑-2-基)乙酸片段晶体结构
描述符：(1,3-苯并噻唑-2-基)乙酸、组蛋白去乙酰化酶6（Histone deacetylase 6）、未知原子或离子……
作者：Harding, R.J.、Halabelian, L.、Ferreira de Freitas, R.、Ravichandran, M.、Santhakumar, V.、Schapira, M.、Bountra, C.、Edwards, A.M.、Arrowsmith, C.M.、结构基因组学联合体（Structural Genomics Consortium, SGC）
数据提交日期：2018-02-11
发布日期：2018-02-28
最后修改日期：2023-10-04
实验方法：X射线衍射（分辨率1.55 Å）
引用文献：《HDAC6锌指泛素结合域抑制剂的鉴定与构效关系》，J. Med. Chem.，第61卷，2018年
创建时间：
2018-02-11
