Crystal structure of L-asparaginase from Thermococcus Sibiricus double mutation D54G/T56Q

Crystal structure of L-asparaginase from Thermococcus Sibiricus double mutation D54G/T56Q Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, GLYCINE, ... Authors: Matyuta, I.O, Varfolomeeva, L.A, Minyaev, M.E, Dumina, M, Zhdanov, D, Zhgun, A, Pokrovskaya, M, Aleksandrova, S, El'darov, M, Popov, V.O, Boyko, K.M. Deposit date: 2025-04-10 Release date: 2025-06-11 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Hyperthermophilic L-Asparaginase from Thermococcus sibiricus and Its Double Mutant with Increased Activity: Insights into Substrate Specificity and Structure. Int J Mol Sci, 26, 2025西伯利亚热球菌（Thermococcus sibiricus）来源的L-天冬酰胺酶（L-asparaginase）D54G/T56Q双突变体的晶体结构。描述：二(羟乙基)醚、甘油、甘氨酸等。作者：Matyuta, I.O、Varfolomeeva, L.A、Minyaev, M.E、Dumina, M、Zhdanov, D、Zhgun, A、Pokrovskaya, M、Aleksandrova, S、El'darov, M、Popov, V.O、Boyko, K.M。沉积日期：2025-04-10；发布日期：2025-06-11；最后修改日期：2025-07-09。测试方法：X射线衍射（分辨率1.9 Å）。引用文献：《嗜热性西伯利亚热球菌来源L-天冬酰胺酶及其高活性双突变体：底物特异性与结构解析（Hyperthermophilic L-Asparaginase from Thermococcus sibiricus and Its Double Mutant with Increased Activity: Insights into Substrate Specificity and Structure）》，发表于《国际分子科学杂志（Int J Mol Sci）》，2025年，第26卷。