RP Stress and Biomarkers

Patients with Retinitis Pigmentosa (RP) commonly experience sleep-related issues and are susceptible to stress. Moreover, variations in their vision are often linked to anxiety, stress and drowsiness, indicating that stress and sleep deprivation lead to a decline in vision, and vision improves when both are mitigated. The objective of this study was to investigate the utility of salivary biomarkers as biochemical indicators of anxiety and sleep deprivation in RP patients.视网膜色素变性（Retinitis Pigmentosa，RP）患者通常存在睡眠相关问题，且易受应激影响。此外，患者的视力波动常与焦虑、应激及嗜睡密切相关，这表明应激与睡眠剥夺会导致视力下降，而当二者得到缓解时，视力可得到改善。本研究旨在探究唾液生物标志物作为RP患者焦虑与睡眠剥夺生化指标的应用价值。