Podoplanin is a marker but no driver for malignant progression in glioblastoma

Genome-wide expression analysis of PDPNhigh and PDPNlow subpopulations of human glioblastoma cells The aim of this expression study was to identify genes that are differentially expressed between the two populations and to determine a PDPN-associated gene signature Six human glioblastoma cultures were sorted for high and low PDPN expression, RNA extracted and genome-wide expression analysis performed