Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
Early and late apoptosis measured by annexin V and propidium iodide staining in human breast cancer cells revealed that the metastatic MDA-MB-231 cells pretreated for 24 h with artesunate, became resi
Aim: Novel thiazole hybrids were synthesized via thiazolation of 4-phenylthiosemicarbazone (4). Materials & methods: The anticancer activity against the NCI 60 cancer cell line panel. Results: Methyl
The IC50 for ligand inhibition of cell proliferation was derived from the antibody dose-titrations curves. The number of replicate experiments is shown parenthesis. ND, not determined.
