The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic f
ENCODES a protein that exhibits amino acid binding; heme binding; oxygen binding; INVOLVED IN response to nitroglycerin; tryptophan catabolic process to acetyl-CoA; tryptophan metabolic process; PARTI
ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN antibiotic metabolic process (ortholog); benzylpenicillin metabolic process (ortholog); canalicular bile acid tr
This allele is a spontaneously missense mutant found in a polycystic kidney diseased male Sprague Dawley rat. The mutation was a C to T transition that replaces an arginine by a tryptophan at amino ac