we evaluated the mechanism behind NOTCH activation in prostate cancer Overall design: GEP analysis of mice WT, Pten pc+/+; Ptenpc-/-; Ptenpc-/- treated with Gamma-secretase inhibitor
Identify LXR target gens that are involved in migration and invasion phenotype Overall design: PC3 prostate cancer cell were treated for 24h with DMSO or GW3965 1µM in RPMI-1640, L-Glu 2mM after overn
Numerous differentially expressed circular RNAs (circRNAs) have been identified; however, their roles have not been fully elucidated. Since dysregulated circRNAs may have clinical applications, it is
Purpose: To examine the effects of proL1 upregulation on global gene expression in LNCaP cells using RNA sequencing (RNA-Seq) Methods: LNCaP cells were transformed to overexpress proL1 using lentivira
