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Matched TCR sequencing of high and low responders to study differences in T cell response
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创建时间：
2022-08-15
相关数据集
Tissue-resident Memory and Circulating T cells are Early Responders to Pre-surgical Cancer Immunotherapy. Tissue-resident Memory and Circulating T cells are Early Responders to Pre-surgical Cancer Immunotherapy
Pre-surgical (neoadjuvant) immune checkpoint blockade has shown promising activity in multiple cancer types, but the molecular mechanisms are not well understood. Here, we characterized early kinetic
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ref_LCMV_CD4_mouse_release_v1.rds
GP66:I-A b+ spleen T cells were sorted from LCMV infected animals either 7 or 21 days after Clone 13 infection, conditions referred to as Early and Late Chronic. In addition, similar populat
Figshare2021-10-12 更新40
CD4 + T cell proliferation following incubation of PBMCs ex vivo with different antigens.
CD4+ T cell proliferation following incubation of PBMCs ex vivo with different antigens.
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Table_1_Naïve Primary Mouse CD8+ T Cells Retain In Vivo Immune Responsiveness After Electroporation-Based CRISPR/Cas9 Genetic Engineering.xlsx
CRISPR/Cas9 technology has revolutionized genetic engineering of primary cells. Although its use is gaining momentum in studies on CD8+ T cell biology, it remains elusive to what extent CRISPR/Cas9 af
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Effect of IL-6 on antigen-specific CD8+ T cell activation in vitro
Interleukin 6 (IL-6) is a pleiotropic cytokine with diverse roles in homeostasis, inflammation, and cancer. Here we performed transcriptional profiling of OT-I CD8+ T cells activated in the presence o
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