Effect of Omomyc on lymph node metastases from melanomas [SkMel147]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE227843
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资源简介：
Skin melanomas are highly aggressive and metastatic. Omomyc is the best MYC inhibitor currently available. We analysed the effect of Omomyc expression in a transgenic and inducible (upon Doxycycline addition) manner in spontaneous lymph node metastases from SkMel147 (mutated in NRAS) melanoma cells in vivo. We used microarrays to detail the change in the gene expression programs induced by Omomyc on day 2. Melanomas from vehicle- or doxycycline-treated mice were excised, RNA extracted and hybridized on Affymetrix microarrays.
创建时间：
2023-04-11
