Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trial

Inhibition of the sodium-hydrogen exchanger (NHE) is a powerful experimental tool to inhibit sodium and calcium accumulation within the ischemic myocyte and halt...钠氢交换体（sodium-hydrogen exchanger，NHE）抑制法是一种强效实验手段，可抑制缺血心肌细胞内钠与钙的蓄积，并阻断……