Additional file 4. Table S2. DMR results. Table S3. Epigenetic age acceleration results. Table S4. Cell count differences. Table S5. Effects of adjustment for mQTL and allele frequency differences. Ta
The highly improved cognitive function is the most significant change in human evolutionary history. Recently, several large-scale studies reported the evolutionary roles of DNA methylation; however,
We mapped DNA methylation in 580 animal species (535 vertebrates, 45 invertebrates), resulting in 2443 genome-scale, base-resolution DNA methylation profiles of primary tissue samples from various org
It has been thought that epigenetic changes underlie the evolutionary divergence of phenotype between closely related species. To study differences in DNA methylation between humans and chimanzees, we