Crystal structure of the thioredoxin reductase apoenzyme from Entamoeba histolytica in the absence of the NADP cofactor

Crystal structure of the thioredoxin reductase apoenzyme from Entamoeba histolytica in the absence of the NADP cofactor Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, THIOREDOXIN REDUCTASE Authors: Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M. Deposit date: 2013-10-25 Release date: 2014-11-05 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.28 Å) Cite: X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action. J.Struct.Biol., 194, 2016

本数据集记录了溶组织内阿米巴（Entamoeba histolytica）来源的硫氧还蛋白还原酶（Thioredoxin Reductase）脱辅酶在缺乏烟酰胺腺嘌呤二核苷酸磷酸（NADP）辅因子时的晶体结构。相关配体组分为：黄素腺嘌呤二核苷酸（FLAVIN-ADENINE DINUCLEOTIDE）、金离子（GOLD ION）、硫氧还蛋白还原酶（Thioredoxin Reductase）。
作者：Parsonage, D.、Kells, P.M.、Hirata, K.、Debnath, A.、Poole, L.B.、McKerrow, J.H.、Reed, S.L.、Podust, L.M.
沉积日期：2013-10-25
发布日期：2014-11-05
最后修改日期：2024-11-20
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率为2.28埃（Å）
引用文献：《溶组织内阿米巴硫氧还蛋白与硫氧还蛋白还原酶的晶体结构及金诺芬作用机制的主流假说》（原标题：X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action），刊载于《结构生物学杂志》（J.Struct.Biol.）194卷，2016年。