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Nonalcoholic fatty liver disease in AxB mice. Mus musculus

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NIAID Data Ecosystem2026-03-06 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA134987
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Spontaneous insulin resistance and NAFLD emerged in AxB F1 male mice with parent-of-origin effects such that AB6F1 (AJ dam x B6 sire) were susceptible whereas B6AF1 (B6 dam x AJ sire) were resistant. We used microarrays to correlate gene expression with the NAFLD phenotype in 9-month-old male AB6F1 (affected) versus B6AF1 (unaffected) mice. Overall design: Whole liver slices from two 9-month-old AB6F1 and B6AF1 males were collected for RNA extraction and hybridization on Affymetrix microarrays.
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2011-01-05
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