Regional mutation density (RMD) signatures obtained after appling NMF into a matrix of mutation density across 1Mb windows along the genome for 4221 tumor samples. The values provided (NMF exposures)
In this study, we sought to indentify stable individual traits in developing metastatic melanoma, assess their stability in time, and analyze typical dynamics and common trends of genomic changes in i
aMinimum 3 genes in the TTP-low tumor gene signature must be targets of the upstream regulator. Top 10 upstream regulators of the TTP-low tumor gene signature.
A key step in pre-mRNA splicing is the recognition of 3ʹ splicing sites by the U2AF large and small subunits, a process regulated by numerous trans -acting splicing factors. How these trans</
