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Crystal structure of the immunoreceptor TIGIT in complex with Poliovirus receptor (PVR/CD155/necl-5) D1 domain

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of the immunoreceptor TIGIT in complex with Poliovirus receptor (PVR/CD155/necl-5) D1 domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor, T cell immunoreceptor with Ig and ITIM domains Authors: Rouge, L, Stengel, K.F, Yin, J.P, Bazan, F.J, Wiesmann, C. Deposit date: 2011-10-28 Release date: 2012-03-14 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.903 Å) Cite: Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering. Proc.Natl.Acad.Sci.USA, 109, 2012

免疫受体TIGIT与脊髓灰质炎病毒受体(Poliovirus receptor, PVR/CD155/necl-5)D1结构域形成复合物的晶体结构 Descriptor: 2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、脊髓灰质炎病毒受体、含Ig和ITIM结构域的T细胞免疫受体(T cell immunoreceptor with Ig and ITIM domains, TIGIT) Authors: Rouge, L、Stengel, K.F、Yin, J.P、Bazan, F.J、Wiesmann, C. Deposit date: 2011-10-28 Release date: 2012-03-14 Last modified: 2024-11-06 Method: X射线衍射(X-RAY DIFFRACTION),分辨率2.903埃 Cite: 结合脊髓灰质炎病毒受体的TIGIT免疫受体结构揭示了依赖顺式-反式受体聚集的细胞黏附与信号转导机制。《美国国家科学院院刊》(Proc.Natl.Acad.Sci.USA),第109卷,2012年
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2011-10-28
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