Determinants of treatment failure and safety profile of extracorporeal shock wave lithotripsy for urolithiasis: A retrospective cohort study

We conducted a retrospective cohort analysis of 941 patients who underwent ESWL for upper tract urolithiasis at a single tertiary care center between January 2018 and May 2023. Treatment success was defined as the absence of fragments >4 mm on follow-up imaging at three months. Demographic, clinical, and stone characteristics were analyzed. Univariate and multivariate logistic regression models were used to identify independent predictors of stone clearance failure and the requirement for auxiliary interventions.本研究于2018年1月至2023年5月期间，在单家三级医疗中心开展了一项针对941例接受体外冲击波碎石术（Extracorporeal Shock Wave Lithotripsy，ESWL）治疗上尿路结石病的回顾性队列研究。本研究将治疗成功定义为术后3个月随访影像学检查未发现直径＞4mm的结石残留碎片。研究对患者的人口学特征、临床资料及结石相关特征进行了分析，并采用单因素与多因素logistic回归模型，识别结石清除失败的独立预测因子以及需接受辅助干预的相关影响因素。