The CKD Optimal Management With BInders and NicotinamidE
收藏DataCite Commons2023-01-13 更新2024-07-13 收录
下载链接：
https://repository.niddk.nih.gov/studies/combine
下载链接
链接失效反馈官方服务：
资源简介：
Phosphorus, a mineral found in many foods, works with calcium and vitamin D to keep bones healthy. Healthy kidneys keep the right balance of phosphorus in the body. Fibroblast growth factor 23 (FGF23) is a hormone that helps the kidneys to control the blood levels of phosphorus.
In people with chronic kidney disease, kidneys struggle to get rid of enough phosphorus, so FGF23 levels increase in the blood to help get rid of extra phosphorus. Over time, with progressive loss of kidney function, both phosphorus and FGF23 can build up in the blood simultaneously. Researchers believe that too much phosphorus and FGF23 in the blood may lead to weak bones, increase the risk of heart problems, and accelerate progression of kidney disease. However, the best way to control phosphorus and FGF23 levels in the blood in patients with chronic kidney disease is not known.
COMBINE is a study to determine new methods to lower serum phosphorus levels and levels of FGF23 in chronic kidney disease patients.
提供机构：
NIDDK Central Repository
创建时间：
2023-01-13
