Fine mapping of the associated pathways and replication of the top SNP.

In the first five columns the analysis of the separate genes is depicted. In the second five columns the single SNP analysis is shown and in the final four columns the replication stage is shown.SNPs (total) indicates the total number of available SNPs in the gene. SNPs (final) indicates the number of SNPs with Pasingle SNP analysis shown in IL6 pathway.bsingle SNP analysis shown in IL2 pathway.cSNP in LD (R2 = 0.52) with rs310219, not selected for replication.dp-value>0.1 of SNP in GENDER, not selected for replication.eSNP in LD (R2 = 0.57) with rs17318918, not selected for replication.fSNP in LD (R2 = 0.54) with rs6006636, not selected for replication.gSNP out of HWE (p = 0.0001) during replication.hSNP did not fit the iPlex designs.