首页/数据集/Table S1 - Ligand-Directed Functional Selectivity at the Mu Opioid Receptor Revealed by Label-Free Integrative Pharmacology On-Target

Table S1 - Ligand-Directed Functional Selectivity at the Mu Opioid Receptor Revealed by Label-Free Integrative Pharmacology On-Target

Figshare2015-12-02 更新2026-04-29 收录

μ-阿片受体

配体功能选择性

数据链接：

https://figshare.com/articles/dataset/Ligand_Directed_Functional_Selectivity_at_the_Mu_Opioid_Receptor_Revealed_by_Label_Free_Integrative_Pharmacology_On_Target/132567 数据链接链接失效反馈

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资源简介：

Opioid ligands, their binding affinity, and references. (PDF)

应用场景：

创建时间：

2015-12-02

μ-阿片受体

组胺H1受体

ABSTRACT The present study was designed to examine the role of Opioidergic and Histaminergic systems on feeding behavior in 3-hour food deprived neonatal meat- type chicks. In experiment 1, chicks rec

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Data from: G protein regulatory network shapes magnitude and kinetics of behavioral responses in an engineered opioid receptor model

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G protein-coupled receptors (GPCRs) control essential neuronal functions. One GPCR with prominent effects on the nervous system and animal behavior is the mu-opioid receptor (MOR). GPCRs mediate the

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Dermorphin Blocks Apneic Response to Intravenous Bolus Injection of Fentanyl

阿片类药物呼吸抑制

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Rapid intravenous injection of overdose fentanyl triggers an immediate sustained apnea (ventilatory arrest), leading to sudden death within a few minutes in humans. Results in this study demonstrate t

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Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ‑Opioid Receptor

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Fluorescently labeled ligands are useful pharmacological research tools for studying receptor localization, trafficking, and signaling processes via fluorescence imaging. They are also employed in flu

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Discovery, Structure–Activity Relationship, and Mechanistic Studies of 1‑((3 R ,4 S )‑3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic

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Management of moderate to severe pain relies heavily on opioid analgesics such as morphine, oxycodone, and fentanyl in clinics. However, their prolonged use was associated with undesirable side effect

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Table S1 - Ligand-Directed Functional Selectivity at the Mu Opioid Receptor Revealed by Label-Free Integrative Pharmacology On-Target

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