Table S1 - Immune Response to Snake Envenoming and Treatment with Antivenom; Complement Activation, Cytokine Production and Mast Cell Degranulation

Patients who had pyrogenic reactions had higher plasma concentrations of IL-6, IL-10 and sTNFRI compared to patients without pyrogenic reactions in both patients with anaphylaxis and patients with no reaction to antivenom. Concentrations of TNFα were also higher in patients with both pyrogenic and anaphylactic reactions to antivenom compared to anaphylaxis alone. * Mediator concentrations significantly higher in patients with pyrogenic reactions (Mann-Whitney). † Mediator concentrations significantly lower in patients with pyrogenic reactions (Mann-Whitney).
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