Palladium(0)-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Substituted β‑Naphthols with Morita–Baylis–Hillman (MBH) Adducts
收藏NIAID Data Ecosystem2026-03-14 收录
下载链接：
https://figshare.com/articles/dataset/Palladium_0_-Catalyzed_Intermolecular_Asymmetric_Allylic_Dearomatization_of_Substituted_Naphthols_with_Morita_Baylis_Hillman_MBH_Adducts/21371141
下载链接
链接失效反馈官方服务：
资源简介：
Pd-catalyzed intermolecular asymmetric allylic dearomatization
of substituted β-naphthol derivatives with Boc-protected Morita–Baylis–Hillman
(MBH) adducts was developed. The reaction occurs smoothly in 1,4-dioxane
at room temperature in the presence of [Pd(C3H5)Cl]2 (2.5 mol %), (S, Sp)-PHOX ligand (5.5 mol %), and Li2CO3 (1.0 equiv). A series of dearomatized products were afforded in
moderate to excellent yields and enantioselectivity (up to 99% yield,
97% ee). Furthermore, the compatibility with gram-scale reaction and
mild conditions make the current method synthetically useful.
创建时间：
2022-10-20
