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Cryptococcus neoformans var. grubbii serotype A (H99) gpp2delta strain

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP226736
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资源简介:
The present study provided the transcriptomic analysis of the C.neoformans gpp2 deletion strain compared to wild type (H99 strain). This gene (GPP2) is involved in osmotic stress, sulfur uptake and oxidative stress response in this oportunistic yeast that causes meningoencephalitis in immunocompromised patients. Deletion of GPP2 causes several phenotypic features related to stress response in C. neoformans and strains that carry this gene deletion are hypovirulent in invertebrate animal model of infection.
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2019-10-24
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