Comparison of relative vascular areas.

Cohorts of rats were treated either with intravenous injections of α1-adrenoceptor antibody (AB) or with subcutaneous injections with α1-adrenoceptor peptide (PEP). Control animals received unspecific control IgG (C-AB) or albumin (C-PEP). Applications of substances were repeated monthly. The time span between TOF-MRA measurement 1 and measurement 2 was eight months. Relative vascular areas were determined by grayscale analysis of two-dimensional TOF-MRA maximum-intensity-projections. Values are given as means ± standard error of the mean. The number of animals of each group is given in brackets.*significantly different to measurement 1 (p