A previous study in this journal used Monte Carlo simulations to compare the power and familywise Type I error rates of ten multiple-testing procedures in the context of pairwise comparisons in balanc
OR is the odds ratio of disease risk for genotype Dd versus genotype dd (assumed to be equal to the odds ratio for genotype DD versus Dd). The disease risk for genotype dd is assumed to be 0.001. Powe
Expected margins of error for 90% confidence intervals (95% one-sided confidence limit) for μA−B from the paired serial t-test for level change in Eq 8; assumes σ2 = 1.
*Effect size, f, was determined using one-way ANOVA to compare multiple groups. #Effect size, d, was determined using Student's t-tests to compare between two groups.
In scenario I, only phenotype 1 is associated with the SNP. rG = 1 or −1 does not affect the simulation results. Only results with rG = 1 are shown.Simulated power under the same simulation scenarios