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A TNIP1-1 driven systemic autoimmune disorder with elevated IgG4

NIAID Data Ecosystem2026-03-14 收录

自身免疫性疾病

TNIP1基因变异

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA939726 数据链接链接失效反馈

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资源简介：

A pathogenic variant in TNIP-1 contributes to autoimmunity with increased IgG4 antibody levels.

应用场景：

创建时间：

2023-02-28

T细胞亚群转录组学

自身免疫性疾病

To test whether human in vitro primed Th9 cells recapitulate the core pathogenic Th2 cell phenotype, we differentiated naïve T cells into Th1 (IL-12), Th2 (IL-4), Th9 (IL-4+TGF-β), and iTreg (TGF-β).

NIAID Data Ecosystem60

Myeloid-derived suppressor cells control B cells within the central nervous system during autoimmunity. Myeloid-derived suppressor cells control B cells within the central nervous system during autoimmunity

自身免疫性疾病

中枢神经系统炎症

Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) have been characterized in the context of malignancies. Here, we show that PMN-MDSCs have the unique capacity to restrain B cells during

NIAID Data Ecosystem20

SLE and atherosclerosis CD8+ T-cell RNAsequencing

自身免疫性疾病

心血管免疫学

SLE and atherosclerosis CD8+ T-cell RNAsequencing

ChEBI2024-10-10 更新10

Autoantibodies levels of subjects included in this study.

自身免疫性疾病

生物标志物检测

(XLSX)

NIAID Data Ecosystem30

Table_4_Role of immune cells in mediating the effect of gut microbiota on Hashimoto’s thyroiditis: a 2-sample Mendelian randomization study.XLSX

自身免疫性疾病

孟德尔随机化

PurposeHashimoto’s thyroiditis (HT) is one of the most commonly encountered types of autoimmune thyroid disorders (AITDs), influenced by environmental factors, genetics, and the immune system. Previou

NIAID Data Ecosystem20

A TNIP1-1 driven systemic autoimmune disorder with elevated IgG4

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