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The liver of high-fat diet-induced NASH mouse model Gut microbiota 16S rRNA

NIAID Data Ecosystem2026-03-13 收录

NASH肠道菌群研究

高脂饮食小鼠模型

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA784743 数据链接链接失效反馈

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资源简介：

This study aimed to investigate the protective effects of mushroom on the gut microbiota in the high-fat diet-induced NASH mouse model.

应用场景：

创建时间：

2021-11-30

高脂饮食小鼠模型

脂肪酸干预实验

Mice were fed a HFC diet either supplemented or not with 0.5% fatty acid for 11 wk. Data are mean ± S.E.M. (n = 10 to 13). * p<0.05 vs. HFC, ** p<0.01 vs. HFC and *** p<0.001 vs. HFC.

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Liver Transcriptomes in C57BL/6 mice

脂肪代谢转录组

高脂饮食小鼠模型

Purpose: a transcriptome analysis was used to ascertain whether lipid metabolism disorders were induced by high-fat diet (HFD), and comparisons were made between control, HFD and DfCS-Ib(treatment) gr

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Metabolic parameters of C57Bl/6 mice fed a low or high fat diet for 12 wk.

高脂饮食小鼠模型

代谢指标比较

All measurements were made in 5 hour fasted mice. Data are mean ± SEM. aP<0.05 vs Chow; bP<0.001 vs Chow. LFD, low fat diet; HFD, high fat diet.

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BA pool size and serum BA concentration in C57BL/6J mice.

高脂饮食小鼠模型

干预效果评估

Ch denotes chow, F denotes HF diet, FCOL denotes HF diet+2% w/w colestimide and FB denotes HF diet+0.5% w/w CA as specified in Fig. 1A. Data are expressed as mean +/− SEM (n = 5–6). AP<0.05 versus F.

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Transcriptomic changes assoicated with hepatic AHR or ARNT loss in female mice challenged with high-fat diet. Transcriptomic changes assoicated with hepatic AHR or ARNT loss in female mice challenged with high-fat diet

肝脏代谢调控

高脂饮食小鼠模型

The aryl hydrocarbon receptor (AHR) is an important hepatic transcription factor that appears to have a role in regulating endogenous liver metabolism. Canonical AHR-mediated regulation of transcripti

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The liver of high-fat diet-induced NASH mouse model Gut microbiota 16S rRNA

资源简介：

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