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The impact of accumulating immune adaptation in circulating strains of HIV-1

NIAID Data Ecosystem2026-05-02 收录

HIV-1免疫适应

病毒进化

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Sanger-based and next-generation sequencing of HIV-1 gag, pol, and nef genes from Western Australian cohorts infected during the early and late stages of the HIV-1 epidemic.

应用场景：

创建时间：

2025-09-01

病毒进化

RNA翻译

RNA translation is the rate-limiting step when cells synthesize proteins. Elevating translation efficiency (TE) is intuitively beneficial. Particularly, when viruses invade host cells, how to compete

DataCite Commons2024-02-14 更新180

Data from: Cell tropism predicts long-term nucleotide substitution rates of mammalian RNA viruses

病毒进化

细胞趋向性

The high rates of RNA virus evolution are generally attributed to replication with error-prone RNA-dependent RNA polymerases. However, these long-term nucleotide substitution rates span three orders o

DataONE2014-01-14 更新110

Support for the 4th domain of life hypothesis [18] from analyses of informational genes using different models.

病毒进化

生命域分类

“Yes” denotes a “4-domains” topology sensu Boyer et al [18] in which the NCLDVs emerge as a monophyletic group branching between Archaea and Eukaryotes; in cases where we report no support, the NCLDVs

NIAID Data Ecosystem70

Rate of novel host invasion affects adaptability of evolving RNA virus lineages

病毒进化

宿主适应性

Although differing rates of environmental turnover should be consequential for the dynamics of adaptive change, this idea has been rarely examined outside of theory. In particular, the importance of R

DataONE2020-06-24 更新120

Recombination and Darwinian selection as drivers of genetic diversity and evolution of sweet potato leaf curl viruses in Tanzania. Complete genome of Sweet potato leaf curl viruses (SPLCVs)

病毒进化

植物病害基因组学

Using a combination of Next-Generation and Sanger sequencing techniques, we detected sweet potato leaf curl viruses (SPLCVs; Genus Begomovirus) and determined their genetic diversities, recombination,

NIAID Data Ecosystem90

The impact of accumulating immune adaptation in circulating strains of HIV-1

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