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Transcription profiling of human melanoma cell lines to identify transcriptional targets of p16INK4A in melanoma

ChEBI2008-06-15 更新2026-07-21 收录

黑色素瘤分子机制

转录靶点识别

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-7153 数据链接链接失效反馈

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资源简介：

Transcription profiling of human melanoma cell lines to identify transcriptional targets of p16INK4A in melanoma

应用场景：

创建时间：

2008-06-15

黑色素瘤分子机制

基因功能注释

Significant GO terms for the top 300 genes that distinguish primary from cutaneous melanoma.

NIAID Data Ecosystem70

m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells. m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells

RNA表观遗传学

黑色素瘤分子机制

N6-methyladenosine (m6A) RNA methylation is the most abundant internal chemical modifications in eukaryotic messenger RNA (mRNA) as well as long non-coding RNA (lncRNA). Recently, m6A RNA methylation

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Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression

黑色素瘤分子机制

DNA损伤检查点

Defects in DNA damage responses may underlie genetic instability and malignant progression in melanoma. Cultures of normal human melanocytes (NHMs) and melanoma lines were analyzed to determine whethe

NIAID Data Ecosystem30

Importance of RAD6B in activation of canonical WNT signaling in melanoma development

黑色素瘤分子机制

Wnt信号通路调控

We have demonstrated that RAD6B, a ubiquitin conjugating enzyme that is a principal component of translesion synthesis pathway, stabilizes and transcriptionally activates beta-catenin by lysine 63-lin

NIAID Data Ecosystem60

Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance

黑色素瘤分子机制

自噬调控

To Study the role of mutant Braf V600E and ERK dependent phosphorylation of TFEB in regulation of autophagy and lysosome biogenesis in the context of melanoma growth and metastasis, we used whole gene

NIAID Data Ecosystem40

Transcription profiling of human melanoma cell lines to identify transcriptional targets of p16INK4A in melanoma

资源简介：

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