Phenotyping HBV-specific and global B cells in HBV infection

Development of a comprehensive B cell flow cytometry panel to assess global and HBV-specific B cells during HBV infection. This experiment was run to test the full panel with all markers including HBV-specific B cell tags in relevant chronic HBV infected subjects to show functionality of the panel in relevant cell types and assess HBV-specific B cell labeling in this context.
Conclusion:
This 24-color flow panel can accurately distinguish all marker populations, including antigen-specific B cell detection.