Structure of mitochondrial bc1 in complex with ck-2-68

Structure of mitochondrial bc1 in complex with ck-2-68 Descriptor: 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-1~{H}-quinolin-4-one, Cytochrome b, Cytochrome b-c1 complex subunit 1, ... Authors: Xia, D, Esser, L, Zhou, F, Huang, R. Deposit date: 2022-02-15 Release date: 2023-02-22 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes. J.Biol.Chem., 299, 2023

与CK-2-68结合的线粒体bc1复合物结构。配体描述：7-氯-3-甲基-2-[4-[[4-(三氟甲氧基)苯基]甲基]苯基]-1H-喹啉-4-酮；涉及蛋白包括细胞色素b（Cytochrome b）、细胞色素b-c1复合物亚基1（Cytochrome b-c1 complex subunit 1）等。作者：Xia D、Esser L、Zhou F、Huang R。存入日期：2022-02-15，发布日期：2023-02-22，最后修改日期：2024-11-06。实验方法：电子显微镜（分辨率2.88埃）。引用文献：《结合抗疟剂CK-2-68的复合物III结构为疟原虫细胞色素bc1复合物的选择性抑制机制提供新见解》，发表于《J.Biol.Chem.》2023年，第299卷。