Basal fasting metabolites and insulin levels.

*P values are from two-way ANOVAs with Scheffe's post-hoc test for difference between groups. Differences between groups remained significant after adjustment for lean body weight, gender or age. However, adjustment for BMI or waist circumference abolished group differences in insulin, triacylglycerol and glycerol levels, but not the other group differences. FH−: no family history of type 2 diabetes; FH+: offspring of both parents with type 2 diabetes; LBM: lean body mass; NEFA: nonesterified fatty acids; PP: postprandial experimental protocol; PP/clamp: postprandial with insulin infusion experimental protocol; T2D: subjects with type 2 diabetes; TG: triacylglycerol.