EGF decreases the abundance of microRNAs that restrain oncogenic transription factors

ChEBI2012-09-06 更新2026-07-21 收录

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MicroRNA调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40626 数据链接链接失效反馈

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EGF decreases the abundance of microRNAs that restrain oncogenic transription factors

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2012-09-06

MOESM2 of NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2

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蛋白质翻译后修饰

Additional file 2: Figure S1. NOS1 blocks IFNα-stimulated gene induction. a SKOV3 and SW480 cells were treated with IFNα for 6 h in the presence or absence of simultaneous GSNO. The mRNA expression of

Figshare2019-12-05 更新20

Activation of Akt/Protein Kinase B Overcomes a G(2)/M Cell Cycle Checkpoint Induced by DNA Damage

细胞周期机制

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Activation of Akt, or protein kinase B, is frequently observed in human cancers. Here we report that Akt activation via overexpression of a constitutively active form or via the loss of PTEN can overc

PubMed Central10

Table4_Integrated Transcriptome and Multiple Activated Pathways in Endometrial Cancer.XLSX

子宫内膜癌转录组

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Because the incidence of endometrial cancer is notably increasing worldwide, it has become the leading gynecologic cancer in the United States. Standard treatment results in the loss of reproductive f

NIAID Data Ecosystem10

In the zip archive, there are three different available versions of the model: File PI3K_AKT_Final_V2.1.cps, physiological model i.e., no B-RAF mutation; File PI3K_AKT_Final_V2.1_A375.cps, A375 cell line model i.e, with B-RAF mutation; File PI3K_AKT_Final_V2.1_A375_Dabrafenib.cps, complete model with both B-RAF mutation and Dabrafenib inhibitor set at the lower dosage.

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药物作用机制建模

(ZIP)

NIAID Data Ecosystem20

Table_2_m5C RNA Methylation Primarily Affects the ErbB and PI3K–Akt Signaling Pathways in Gastrointestinal Cancer.XLS

胃肠道癌症m5C甲基化

癌症信号通路

5-Methylcytosine (m5C) is a kind of methylation modification that occurs in both DNA and RNA and is present in the highly abundant tRNA and rRNA. It has an important impact on various human diseases i

NIAID Data Ecosystem10

EGF decreases the abundance of microRNAs that restrain oncogenic transription factors

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